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Polymeric microneedles based enzymatic electrodes for electrochemical biosensing of glucose and lactic acid

Titolo:  Polymeric microneedles based enzymatic electrodes for electrochemical biosensing of glucose and lactic acid
Autori:    A. Caliò, P. Dardano, Vincenza Di Palma, M.F: Bevilacqua, Andrea Di Matteo, H.Iuele
Rivista:     Sensor and Actuators B
Anno di Pubblicazione:   2016
Volume: 236
Pagine:    343-349
Abstract: “Polymeric microneedles (MNs) based working electrodes are fabricated by standard photolithographyof poly(ethylene glycol) diacrylate (PEGDA) doped by enzyme, redox mediator and photoinitiator. Thisflexible device acts as working electrode in electrochemical detection of glucose and lactic acid in solutionwhen glucose oxidase (GOx) and lactose oxidase (LOx) enzymes, respectively, are used. Biosensor showeda linear response in the ranges from 0 to 4 mM and from 0 to 1 mM, for glucose and lactic acid, respectively.A limit of detection equal to 1  M is found. The developed technology has been patented.“